Xbox head Phil Spencer has explained during a Q&A at Microsoft's Build 2016 conference why Halo 5 likely won't be coming to PC. He also touched on why some games will remain exclusive to specific platforms, stating that Microsoft published games will be released on platforms that make sense, using Ashes of the Singularity on PC as an example.
That's not to say Microsoft plans to only publish titles on a single platform. Forza 6, Quantum Break and Rise of the Tomb Raider are perfect examples of games working on multiple systems. It's more to avoid experiences that won't really work on different platforms (or weren't developed with them in mind).
As for Halo 5, which is a first-person shooter (we have many on the PC), Spencer explained that the latest instalment was designed from the get-go for consoles. Halo Wars 2 on-the-other-hand is being developed for both PC and Xbox One. While it's not a definitive "no" for Halo 5, but it's not looking likely. That said, Microsoft could have PC Halo plans with regards to 6 and beyond so we'll have to see.
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Rich Edmonds was formerly a Senior Editor of PC hardware at Windows Central, covering everything related to PC components and NAS. He's been involved in technology for more than a decade and knows a thing or two about the magic inside a PC chassis. You can follow him on Twitter at @RichEdmonds.