Best motherboard for AMD Ryzen 5 5600X in 2021

AMD Ryzen 5 5600X motherboards may be mid-tier, but they can stretch their legs with an X570 chipset-touting motherboard like the ASUS ROG Strix X570-E. Not only would you be able to overlock the CPU without issue, but you also enjoy PCIe 4.0 support, high-quality components, Wi-Fi 6, and Gen 4 M.2 slots capable of unidirectional transfer speeds up to 64GB/s, rapid LAN ports, and plenty of RGB options to light up your office.

While not quite as advanced as our top pick, the A520 AORUS Elite from Gigabyte is still worth considering for your Ryzen 5 5600X. It doesn't come with PCIe 4.0 support but comes with a decent VRM setup, M.2 slot, and will work perfectly fine with your Ryzen 5000-series CPU. You'll also save some money for other components.

The MSI MPG B550 Gaming Edge Wi-Fi may have a mid-range chipset from AMD, but this motherboard has some killer features. You've got 2.5Gb LAN, Wi-Fi 6, decent VRM and actual cooling, PCIe 4.0, M.2 slots with one thermal pad, and a 10+2+1 power phase design.

ASUS ROG Strix X570-I Gaming is a worthy motherboard for more compact PC builds. It's a mini-ITX board, rocking fewer DIMM slots for RAM, fewer PCIe slots, and some other omissions, but still manages to come with an 8+2 phase power delivery design and adequate VRM cooling. There's even PCIe 4.0 support.

NZXT makes some killer PC cases, but the company also makes some exceptionally well-designed motherboards. The NZXT N7 B550 may not have the class-leading X570 chipset, but it doesn't need it. You're getting plenty of expansion points, more fan headers than you'll likely require, and a layout that'll look amazing in most PC builds. NZXT pushed the B550 chipset to its limit with the N7.

ASUS proved X570 motherboards don't have to cost too much compared to other chipsets. The ASUS Prime X570-P has all the bells and whistles you'd usually find on an X570 board but comes with a lower price. You'll be able to enjoy solid VRMs with passive cooling, PCIe 4.0 support, and high-quality components.

This is a motherboard you likely won't need or be able to afford, but it's an insane foundation for a powerful and enthusiast PC build. ASUS held nothing back with the ROG X570 Crosshair VIII Formula, allowing you to do some serious overclocking. There are some high-quality components throughout the board, as well as a heatsink block that can hook up to your water-cooling loop.