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Best Motherboards for AMD Ryzen Threadripper 3990X in 2022

AMD Threadripper 3990X
AMD Threadripper 3990X (Image credit: AMD)

AMD managed to pack 32 cores on the Threadripper platform, allowing enthusiasts to enjoy massive amounts of performance with a physical single processor. Unlike Ryzen processors, Threadripper CPUs require a motherboard with a TRX40 socket and we've rounded up some of the best motherboards for you to consider.

Gigabyte Aorus Pro WiFi (opens in new tab)

Entry TRX40

It's priced way above what you'd normally payout on an AM4 motherboard, but this TRX40 board is actually one of the more affordable options for Threadripper 3000 series processors. This thing comes equipped with M.2 slots, 12+2 phase VRM design, as well as eight RAM slots.

ASUS ROG Zenith II Extreme (opens in new tab)


This is a motherboard you won't need to consider unless you truly require the advanced features and additional enhancements that are present. If you're all about overclocking and really pushing your system to its limit, this platform lets you install up to five M.2 solid-state drives (SSD) installed, and the board comes with USB 3.2 Gen 2 and AMD StoreMI, as well as plenty of premium components.

Gigabyte Aorus Master (opens in new tab)

Value Pick

This is the middle ground in our collection, striking a good balance between features and price. You can enjoy a more advanced VRM setup compared to the Aorus Pro, as well as some other enhancements like a 16 phase power delivery design for a stable and powerful PC.

MSI Creator (opens in new tab)

For Creators

MSI designed this board with creators in mind, rocking a 10Gb LAN port, Wi-Fi 6 support, numerous USB slots, nine fan headers for all your cooling needs, active cooling for the chipset, 16 phase power design, and even a bundled expansion card for a further four PCIe Gen 4.0 M.2 slots.

ASUS ROG Strix TRX40-E Gaming (opens in new tab)

Sleek Design

This ASUS motherboard is all about creating the most unique looking PC around with plenty of headers and ports for cooling and RGB lighting. There's also an addressable OLED display, three M.2 slots, USB 3.2 Gen 2, active 16 stage VRM cooling, Wi-Fi 6, and a handy BIOS.

Choosing the best TRX40 motherboard

Unfortunately, if you're considering one of the newer Threadripper processors, you're going to need to part with some serious cash for the motherboard too. The TRX40 platform is now and pricey, but required for 3000 series Threadripper CPUs. If you're looking for a solid value option, the Gigabyte Aorus Pro WiFi (opens in new tab) is your best bet.

If you want to create a fancy-looking PC build, the ASUS ROG Strix TRX40-E Gaming (opens in new tab) is a better option with addressable RGB headers, an OLED display built right into the motherboard, as well as more important features like active 16 stage VRM cooling, as well as chipset cooling, for better system stability.

Rich Edmonds
Rich Edmonds

Rich Edmonds is Senior Editor of PC hardware at Windows Central, covering everything related to PC components and NAS. He's been involved in technology for more than a decade and knows a thing or two about the magic inside a PC chassis. You can follow him over on Twitter at @RichEdmonds.