Best Left-handed Mouse in 2022

Comfortable, quality mice aren't exclusive to right-handers. The majority might be designed this way, but the good news for left-handers is that you're in no way left out. One of the best mice for right-handed people, the Razer Deathadder Essential is also available in a left-handed design, and that's great news for you.

Razer Deathadder Essential

As good as ever but for left-handers

Who should buy the Razer Deathadder

Why you can trust Windows Central Our expert reviewers spend hours testing and comparing products and services so you can choose the best for you. Find out more about how we test.

Anyone looking for a brilliant left-handed mouse. You don't have to be a gamer, but if you are, you have the bonus of Razer's companion software to really help you get the most from it.

Is it a good time to buy the Razer Deathadder

Absolutely. The Deathadder is one of Razer's most popular mice and there are no signs of any imminent replacement. However, it's unavailable at a lot of third-party retailers, like Best Buy, and can only be found used on Amazon. It's also unavailable at Razer's website, so it's a tough find.

An iconic mouse designed for left-handed people

Razer didn't just settle for ambidextrous mice like the Lancehead, instead specially designing the Deathadder, its most iconic mouse, for left-handed use. That alone gives it massive appeal, as it's designed to be as comfortable to use in the left hand as it is in the right.

The Deathadder is properly designed for left-handed use, a rarity in itself

The Deathadder has a really great ergonomic design. It sits within your palm, with grippy rubber panels on each outer edge, and the additional function buttons right by your thumb. That is to say, it's absurdly comfortable

It lights up if you want it to with Razer's Chroma system, or you can turn it off entirely. The company's incredibly accurate sensor is found on the underside, and whether you're working or playing, the Deathadder tracks perfectly. Five programmable buttons allow you to customize your gaming layout and you can even calibrate for your particular mousepad in the Synapse companion application.

It's well priced, well made, and all the mouse you could every need. It's just tough to find at some retailers. It's not available on Razer's website, for example, and is either only available used or expensive at third-party retailers like Amazon.

Alternatives to the Razer Deathadder Essential

The Deathadder is a truly great mouse, but it's not the only one worth attention. Whether you're looking for something even more ergonomic, more affordable or for some more serious gaming, there's a left-handed mouse for you.

Evoluent VerticalMouse 4

A more natural way to use a mouse

Reasons to buy

Ergonomic design
Quality build
Excellent sensor
Good for gaming and everyday use

Reasons to avoid

Only comes wired
Not available at a lot of retailers

Besides being better for your body, you get an adjustable sensor, a total of six buttons, and a nice sturdy design that will stand the test of time. It's a little pricey but your wrist will thank you for it.

Logitech G300s

An absolute bargain of a mouse

It has a gaming-grade optical sensor which is precise and responsive, as well as a grand total of nine customizable buttons. Logitech's companion software is easy to use, and with onboard memory for up to three profiles, you can take it wherever you go and always have the perfect setup.

SteelSeries Sensei 310

A smaller mouse with some neat features

It has super-low latency, really accurate tracking, and weighs less than 100g. It's perhaps not for folks with large hands, but it's a really well designed and will probably last you a long time.

Bottom line

Whatever your use case, the Razer Deathadder Essential is the mouse to use, it's not just for gamers; it's incredibly comfortable to use, and thanks to its customization features through the Synapse application, you can really make it your own.

Razer Deathadder Essential

As good as ever but for left-handers
Richard Devine
Managing Editor - Tech, Reviews

Richard Devine is a Managing Editor at Windows Central with over a decade of experience. A former Project Manager and long-term tech addict, he joined Mobile Nations in 2011 and has been found on Android Central and iMore as well as Windows Central. Currently, you'll find him steering the site's coverage of all manner of PC hardware and reviews. Find him on Mastodon at