Best Left-handed Mouse in 2022
At Windows Central we use a lot of PC mice, just about all the best ones around so we know the good, the bad and the ugly. When we say a mouse is the best, you know we're on the money.

Comfortable, quality mice aren't exclusive to right-handers. The majority might be designed this way, but the good news for left-handers is that you're in no way left out. One of the best mice for right-handed people, the Razer Deathadder Essential is also available in a left-handed design, and that's great news for you.
Razer Deathadder Essential
Who should buy the Razer Deathadder
Why you can trust Windows Central
Anyone looking for a brilliant left-handed mouse. You don't have to be a gamer, but if you are, you have the bonus of Razer's companion software to really help you get the most from it.
Is it a good time to buy the Razer Deathadder
Absolutely. The Deathadder is one of Razer's most popular mice and there are no signs of any imminent replacement. However, it's unavailable at a lot of third-party retailers, like Best Buy, and can only be found used on Amazon. It's also unavailable at Razer's website, so it's a tough find.
An iconic mouse designed for left-handed people
Razer didn't just settle for ambidextrous mice like the Lancehead, instead specially designing the Deathadder, its most iconic mouse, for left-handed use. That alone gives it massive appeal, as it's designed to be as comfortable to use in the left hand as it is in the right.
The Deathadder is properly designed for left-handed use, a rarity in itself
The Deathadder has a really great ergonomic design. It sits within your palm, with grippy rubber panels on each outer edge, and the additional function buttons right by your thumb. That is to say, it's absurdly comfortable
It lights up if you want it to with Razer's Chroma system, or you can turn it off entirely. The company's incredibly accurate sensor is found on the underside, and whether you're working or playing, the Deathadder tracks perfectly. Five programmable buttons allow you to customize your gaming layout and you can even calibrate for your particular mousepad in the Synapse companion application.
It's well priced, well made, and all the mouse you could every need. It's just tough to find at some retailers. It's not available on Razer's website, for example, and is either only available used or expensive at third-party retailers like Amazon.
Alternatives to the Razer Deathadder Essential
The Deathadder is a truly great mouse, but it's not the only one worth attention. Whether you're looking for something even more ergonomic, more affordable or for some more serious gaming, there's a left-handed mouse for you.
Evoluent VerticalMouse 4
Reasons to buy
Reasons to avoid
Besides being better for your body, you get an adjustable sensor, a total of six buttons, and a nice sturdy design that will stand the test of time. It's a little pricey but your wrist will thank you for it.
Logitech G300s
It has a gaming-grade optical sensor which is precise and responsive, as well as a grand total of nine customizable buttons. Logitech's companion software is easy to use, and with onboard memory for up to three profiles, you can take it wherever you go and always have the perfect setup.
SteelSeries Sensei 310
It has super-low latency, really accurate tracking, and weighs less than 100g. It's perhaps not for folks with large hands, but it's a really well designed and will probably last you a long time.
Bottom line
Whatever your use case, the Razer Deathadder Essential is the mouse to use, it's not just for gamers; it's incredibly comfortable to use, and thanks to its customization features through the Synapse application, you can really make it your own.
Razer Deathadder Essential
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Richard Devine is a Managing Editor at Windows Central with over a decade of experience. A former Project Manager and long-term tech addict, he joined Mobile Nations in 2011 and has been found on Android Central and iMore as well as Windows Central. Currently, you'll find him steering the site's coverage of all manner of PC hardware and reviews. Find him on Mastodon at mstdn.social/@richdevine