The Logitech MX Vertical.Source: Windows Central

Best Vertical Mouse for Carpal Tunnel Windows Central 2021

Vertical mice are an excellent product for people who struggle with carpal tunnel pain while using the computer, and they're also an excellent choice if you want to avoid this problem down the line. There are a wide variety of vertical mice on the market. Still, we think the best one is the Logitech MX Vertical due to its excellent performance, incredibly comfortable design, and high-quality build. It may be one of the most expensive vertical mice available, but it's worth every penny.

Best Overall: Logitech MX Vertical

The Logitech MX Vertical.Source: Logitech

The best overall vertical mouse out there is the Logitech MX Vertical, due to its excellent blend of performance, comfort, and style. Its top-notch optical sensor is incredibly accurate and has a solid DPI range of 400 to 4,000, and the mouse itself has a sleek, curvaceous design that also includes a thumb rest on the left side, giving your hand superb support.

The area your hand grips during use is made out of a soft, felt-like material that's comfortable to the touch, while the mouse buttons are clicky and responsive. Its battery is fantastic, too, and can last up to three weeks on a full charge. Lastly, the forward and back buttons, DPI switch button, and the mouse wheel can all be reprogrammed using Logitech's free Options software.


  • Fantastic comfort and support
  • Incredible performance
  • Button remapping
  • Looks awesome


  • Expensive

Best Overall

The Logitech MX Vertical.

Logitech MX Vertical

King of the hill

The Logitech MX Vertical is a fantastic blend of performance, comfort, and style if you're looking for a vertical mouse.

Best for Gaming: ZLOT RGB Wired Vertical

The ZLOT RGB Wired Vertical.Source: ZLOT

If you're looking for something that's best suited for gaming, then the ZLOT RGB Wired Vertical should be your pick. It's not as comfortable as the Logitech MX Vertical, but it has a few features that come in handy for gamers, such as a high max DPI of 10,000, 11 customizable buttons, and a joystick. On top of that, the optical sensor is accurate and responsive, and the device even comes with some cool RGB lighting that you can customize.


  • Supportive
  • Great performance
  • Lots of customizable buttons
  • More affordable
  • RGB lighting


  • Less comfortable than others

Best for Gaming

The ZLOT RGB Wired Vertical.

ZLOT RGB Wired Vertical


This vertical mouse is best suited for gaming due to its button remapping focus and high DPI maximum.

Best for Big Hands: AUTLEY Wireless Vertical

The AUTLEY Wireless Vertical.Source: AUTLEY

If your hands are unusually large, you'll likely find the AUTLEY Wireless Vertical to be your best bet. It's got a bulkier, thicker design that offers excellent comfort and support for big hands. Like the Logitech MX Vertical, it uses a rechargeable battery that lasts about a week on a charge. The DPI range is average at 800 to 1,600, but the sensor is accurate. Ultimately, this is a specialized mouse that will suit people with large hands only. It's also just as affordable as our favorite budget option, so you don't have to spend much to get it — in fact, it's currently on sale for Black Friday.


  • Design is perfect for big hands
  • Good performance overall
  • Very affordable


  • Battery life is shorter
  • No customizable buttons

Best for Big Hands

The AUTLEY Wireless Vertical.

AUTLEY Wireless Vertical

I like 'em big

Though it lacks advanced capabilities, this mouse offers excellent performance for people with large hands.

Best for Small Hands: Jelly Comb Wireless Vertical

The Jelly Comb Wireless Vertical.Source: Jelly Comb

If your hands are on the small side, don't pass up a chance to get Jelly Comb's wireless offering. It's essentially the same mouse as the AUTLEY one in most respects, except it's a lot smaller and has a different battery. Unlike the other battery-requiring mice on this list that use built-in rechargeables, this mouse uses AA batteries. A full battery will last this mouse a few months, so as long as you don't mind buying AAs every so often, you won't need to worry about it dying out. This mouse is also the most affordable one on the list, too, though it's not the best budget option in terms of quality. Like the AUTLEY Wireless Vertical, it's also on sale for Black Friday right now.


  • Design is perfect for small hands
  • Good performance overall
  • Most affordable
  • Great battery life


  • Requires AA batteries
  • No customizable buttons

Best for Small Hands

The Jelly Comb Wireless Vertical.

Jelly Comb Wireless Vertical

Small package, big value

If you have small hands and don't mind using AA batteries, this compact and capable mouse is right up your alley.

Best Budget: VicTsing Wireless Vertical Mouse

VicTsing Wireless MouseSource: VicTsing

If you're looking to get your hands on a quality, well-rounded vertical mouse for a low price, the VicTsing Wireless Vertical Mouse is a fantastic choice. It provides tons of comfort and support, excellent performance, and a DPI maximum of 1,600. Additionally, it also gets a 12-16 month battery life off one AA battery, which is awesome. While the buttons on the back are placed a little awkwardly, and none of the buttons can be remapped, this mouse is nevertheless a fantastic option if you need to save money, especially since this mouse is also on sale for Black Friday.


  • Supportive design
  • Good performance overall
  • Very affordable
  • Stellar battery life


  • Back buttons placed awkwardly
  • No customizable buttons

Best Budget

VicTsing Wireless Mouse

VicTsing Wireless Vertical Mouse

Affordable and effective

This mouse is incredible if you're looking to save money while also getting great value.

Bottom line

Vertical mice are some of the most helpful PC accessories out there. They can do a ton of work to reduce the symptoms of carpal tunnel or even prevent it from developing in the first place. If you're worried about carpal tunnel, don't hesitate to get a vertical mouse.

Vertical mice come in tons of different shapes, sizes, and qualities. In truth, all of the vertical mice on this list are great, and it was a challenge to call just one of them the best vertical mouse for carpal tunnel. However, we think that the best one out there overall is the Logitech MX Vertical since it has top-notch performance, a beautiful design that makes the user experience significantly more comfortable than other mice, and a sleek, stylish build that everyone will love. It's expensive, but it's an investment you won't regret.

If you're interested in checking out other types of mice, don't miss our roundup of all the best wireless mice and the best PC gaming mice.

Credits — The team that worked on this guide


Brendan Lowry is a Windows Central writer with a burning passion for video games, of which he's been an avid fan since childhood. He's relatively new to the writing scene, but he counters that lack of experience with a rock-solid work ethic and a desire to improve at every opportunity. You'll find him doing reviews, editorials, and general coverage on everything Xbox and PC. Follow him on Twitter.

We may earn a commission for purchases using our links. Learn more.