Best overall

Razer Naga Hex V2

Razer's second version of the popular Naga Hex mouse ($65) has seven buttons on the side instead of six. Combine that with its great ergonomics and performance, and the Naga Hex remains our absolute favorite when it comes to Massive Online Battle Arena (MOBA) mice. It's comfortable, feature-rich and offers excellent performance tailored for MOBA gaming.

Bottom line: It's a stunning all-around mouse designed for gaming in MOBAs.

One more thing: You should take full advantage of Synapse software with other Razer peripherals.

Why the Razer Naga Hex V2 is the best MOBA mouse

The original Naga Hex enabled gamers to develop their skills in MOBA titles at a faster rate, thanks to its performance, functionality and neat button array on the side. That button wheel allowed for a total of six buttons to be programmed, depending on the title in play. League of Legends and DOTA players could bind item slots to a button and free up finger mashing for ability keys.

The second-gen Naga Hex packs a 16,000-DPI laser sensor and an improved seven-button thumb wheel. It also supports Chroma technology. Essentially, it's a modern replacement for the original Naga Hex, with RGB lighting and other features that are now the norm in Razer mice and keyboards. Overall, it has 14 programmable buttons, which is key here. (Pardon the pun.)

In addition to the 16,000-DPI sensor, the mouse can track up to 210 inches per second with 50G acceleration. It's accurate and precise through both slow and fast movements, with 1,000Hz ultra polling and a response time of just one millisecond. The company also kept a similar style with familiar ergonomics for veterans of the original pointer.

Best Wireless

Logitech G602

Utilizing advanced power saving and Delta Zero technology, which is essentially fancy Logitech sensors, the G602 ($35.99) offers up to 250 hours of battery life on a single charge. Its wireless capabilities allow for more freedom when frantically scrolling across the screen to click on enemy characters, and the array of buttons offers high levels of customization.

Bottom line: It's a superb mouse that fits the bill for MOBA and MMO titles, with numerous programmable buttons.

One more thing: It's wireless!

Best Hybrid

Corsair Scimitar Pro RGB

The Scimitar ($79.99) by Corsair is a powerful device with a 12,000-DPI sensor. Dynamic multi-color backlighting is complemented by full CUE integration. Much like the Naga Hex, the Scimitar offers a super-quick response time of just one millisecond, with quick polling and high levels of accuracy.

Bottom line: It's a great mouse for MOBA gaming and some MMO action. This mouse is ideal if you often switch between the two genres.

One more thing: The CUE link can hook this mouse up to Corsair's keyboards and headsets.

Best comfort

SteelSeries Rival 600

The Rival 600 is a kick-ass mouse from SteelSeries. It sports the company's own TrueMove3 sensor with a secondary sensor. That's a dual setup with one being dedicated to detecting when you lift the mouse off the surface, which makes it much more accurate, even when you're re-adjusting your arm placement. It's also comfortable to use and this is enhanced by the two weight covers that house small slabs of metal to make the mouse feel just right.

Bottom line: The Rival 600 not only looks good but has solid ergonomics for long gaming sessions, which makes it a breeze to use.

One more thing: It has on-the-fly DPI switching, up to 12,000.

Conclusion

The best mouse for anything can depend a little on personal preference. A certain mouse you purchase may not feel just right. That said, this collection of mice really are among the best of the best out there, especially if you plan on playing a few MOBAs.

Best overall

Razer Naga Hex V2

Razer's second version of the popular Naga Hex mouse ($65) has seven buttons on the side instead of six. Combine that with its great ergonomics and performance, and the Naga Hex remains our absolute favorite when it comes to MOBA mice. It's comfortable, feature-rich and offers excellent performance tailored for MOBA gaming.

Bottom line: It's a stunning all-around mouse designed for gaming in MOBAs.

One more thing: You should take full advantage of Synapse software with other Razer peripherals.

Updated July 13, 2018: We looked over this guide and made a few edits to continue offering the best in the industry.